Acid Phosphatase Isoenzymes in Bone Tumors
نویسندگان
چکیده
منابع مشابه
Alkaline phosphatase isoenzymes in plasma in hyperthyroidism.
Alkaline phosphatase (ALP; EC 3.1.3.1) isoenzymes were measured in the plasma of 63 untreated hyperthyroid patients (the hyperthyroid group), 58 treated hyperthyroid patients, and 100 blood donors. Total, liver, and bone ALP activities were significantly higher in the hyperthyroid group than in the treated hyperthyroid group or the blood donors. Bone ALP was more frequently and more markedly ab...
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BY CELLULOSE ACETATE OR ACRYLAMIDE GEL ELECTROPHORESIS IT IS POSSIBLE TO SEPARATE THESE ALKALINE PHOSPHATASE ISOENZYMES FROM SERUM: [anode] fast liver, slow liver, placenta/Regan, bone, intestine, bile [cathode]. Heat or chemical inhibition can confirm the differentiation. Normal adult serum always contains slow-liver isoenzyme, and sometimes bone isoenzyme: the latter is always present in seru...
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A new isoenzyme of alkaline phosphatase (EC 3.1.3.1) has been reported to occur in sera from patients with lymphoproliferative diseases. This enzyme is character ized by an inability to hydrolyze cysteamine S-phosphate. We find that the 5,5 -dithobis(2-nitrobenzoic acid)-coupled assay method for cysteamine S-phosphate hydrolysis is not suitable for serum, and we were unable to confirm the exist...
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Background: The most frequent sites of metastases in prostatic carcinoma are bones. Bone scintigraphy is the diagnostic tool of first choice for staging bone metastases in cancer of the prostate. But this examination is expensive and time-consuming.Therefore we are looking especially for serum parameters like alkaline phosphatase, the isoenzyme of bone-specific alkaline phosphatase, and prostat...
متن کاملTwo new methods for separating and quantifying bone and liver alkaline phosphatase isoenzymes in plasma.
We describe two new methods for the separation and quantification of the bone and liver isoenzymes of alkaline phosphatase (EC 3.1.3.1) in plasma. In the first, we use wheat-germ lectin to precipitate the bone isoenzyme. About 80% of this, but minimal liver isoenzyme, is precipitated. The activity of the bone isoenzyme is calculated from measuring the alkaline phosphatase activity in the precip...
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ژورنال
عنوان ژورنال: Orthopedics & Traumatology
سال: 1972
ISSN: 1349-4333,0037-1033
DOI: 10.5035/nishiseisai.21.42